Serie parodique des enquêtes de Conan Doyle Les célèbres méthodes scientifiques de Holmes sont tournées en dérision par des situations absurdes et hilarantes. Les personnages sont tous caricaturés de manière importante : ainsi Holmes est beaucoup trop sûr de lui et imbu de sa personne, Watson un colérique beaucoup plus célèbre que Holmes ce qui gêne beaucoup ce dernier, l'inspecteur Lestrade un imbécile, madame Hudson une vieille alcoolique spécialiste de repas immangeables, le professeur Moriarty un monomaniaque obsédé par l'idée de se venger de Holmes (et réciproquement).
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