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Shirotani est un jeune homme brillant atteint de mysophobie (peur d'être contaminé par des microbes). Quand le chef d'entreprise pour lequel il travaille est victime d'un accident, il rencontre Kurose, un jeune homme qui lui conseille de se faire soigner et lui laisse la carte d'une clinique psychiatrique. Le lendemain, Shirotani se rend à la clinique et comprend que Kurose est un des psychiatres qui y travaillent. Les deux hommes noueront alors une relation qui dépasse bientôt le cadre médecin-patient.
Katsuya Asano, un profiler formé aux Etats-Unis, est amené à travailler pour la police de Tokyo afin de fournir le profil d'un tueur en série qui sévit depuis plusieurs années. Grâce à son aide, l'opération est une réussite et Shinohara Keiji est enfin arrêté. Obnubilé par la personne qui est à l'origine de son arrestation, ce dernier accepte de faire des aveux complets, mais à la condition que Katsuya soit celui qui les recueille. À peine le jeune profiler vient-il d'accepter qu'il est tourmenté nuit après nuit par le même cauchemar : un homme dont il ne voit pas le visage le retient prisonnier et le torture tout en lui murmurant à l'oreille qu'il l'aime. La frontière entre rêve et réalité s'effondre alors brutalement pour lui...
Yû, nouvelle élève de 1re année au lycée Tohmi Higashi, n'est jamais tombée amoureuse. Un jour, elle aperçoit Tôko Nami, membre du conseil des élèves, en train de rejeter un garçon lui déclarant sa flamme. Yû pense avoir enfin trouvé quelqu'un comme elle. Quelqu'un qui n'a jamais connu l'amour et qu'aucune déclaration n'a jamais ému. Mais elle va vite déchanter lorsque cette dernière lui adresse ces quelques mots... « Je crois que je pourrais t'aimer, toi. »
