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Atropos, Clotho et Lachésis veillent aux fils du destin de chacun. Malheureusement, lors d'une de leur dispute, elles altèrent celui d'Ulysse. Pour éviter le courroux d'Athéna, il leur faut réparer ce fil homérique en se mettant en quête de tous les gènes qui ont amené à son développement. Leur odyssée retracera ainsi l'histoire évolutive de la lignée humaine.
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