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A la fin du XVIIe siècle, Johann, initié à l'alchimie par son grand-père, se rend à Berlin pour étudier auprès d'un maître apothicaire. Son destin croisera alors celui d'une mystérieuse confrérie ayant pour emblème La Rose et la Croix, une confrérie recherchant le secret de la pierre philosophale, source de pouvoir et d'immortalité.
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