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Rapatrié d'Afghanistan à cause d'une blessure et de troubles psychologiques, le Dr. Watson retrouve un vieil ami de l'époque de la faculté de médecine qui lui présente son futur colocataire. D'un seul coup d'oeil, cette personne devine qu'il s'agit d'un médecin militaire de retour du Moyen-Orient, qu'un de ses proches est victime d'alcoolisme ou encore qu'il est suivi par un thérapeute. Le nom de ce colocataire ? Sherlock Holmes.
L'histoire se déroule en Allemagne, en 1986, à Düsseldorf. Kenzo Tenma, le personnage principal, est un jeune neurochirurgien très talentueux, destiné à une brillante carrière et fiancé à la fille du directeur de l'hôpital, Eva Heinman. Mais un jour il refuse de soigner le maire et préfère soigner un garçon blessé d'une balle dans la tête. Sa sœur jumelle est aussi internée dans l'hôpital car elle est très choquée. Leurs parents (adoptifs) ont été assassinés sauvagement. Le garçon s'en sort, mais le maire meurt, faute de soins. Tenma est alors rétrogradé par le directeur de l'hôpital et Eva le quitte. Peu de temps après, le garçon et sa sœur disparaissent. Neuf ans plus tard alors que Tenma est sur le point de devenir le directeur d'hôpital, il est accusé de meurtre qui ont en fait été commis par Johann, ce garçon de 11 ans qu'il avait sauvé. Dès lors l'inspecteur Rünge, un homme de caractère et de confiance prend en charge l'enquête. Il poursuit Tenma sans relâche tandis que ce dernier poursuit Johann ; car Tenma, qui se demande s'il n'a pas sauvé un "Monstre", sait que les meurtres sont "l'œuvre" de son ancien patient.
Keita Kurokôchi est membre de la deuxième brigade d’investigation. C’est un inspecteur corrompu dont la connaissance des pires secrets des politiciens et hommes d’affaires de la préfecture lui confère un pouvoir énorme. Ce flic fait horreur au novice Shingo Seike, officier envoyé par l’agence de la police nationale. Mais le jeune policier découvre bientôt chez le vieux ripou un objectif colossal que nul ne soupçonne ! Découvrez un polar haletant qui vous entraînera dans les mystères enfouis du Japon contemporain !
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