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1512. Nicholas Copernic vient à Ferrare pour y donner plusieurs conférences devant un parterre de jeunes gens les plus érudits d'Europe. Mais la célèbre université est en émoi en raison du récent suicide d'un étudiant. Un brillant et jeune agitateur du nom pompeux de Paracelse est persuadé qu'il s'agit d'un crime, et il entend bien le prouver à la police locale remplie d'incapables.
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