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Simon Bacamarte, aliéniste diplômé, s'installe dans une paisible bourgade brésilienne et, au nom de la science, fonde un asile d'aliénés. Il commence par enfermer et classer les lunatiques, mais ne s'arrête pas là. Son emprise sur la population est telle que bientôt toute la ville est internée. L'aliéniste est-il celui qui soigne la folie, celui qui la fabrique, ou celui qui la porte en lui ?
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