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L'histoire se déroule en Allemagne, en 1986, à Düsseldorf. Kenzo Tenma, le personnage principal, est un jeune neurochirurgien très talentueux, destiné à une brillante carrière et fiancé à la fille du directeur de l'hôpital, Eva Heinman. Mais un jour il refuse de soigner le maire et préfère soigner un garçon blessé d'une balle dans la tête. Sa sœur jumelle est aussi internée dans l'hôpital car elle est très choquée. Leurs parents (adoptifs) ont été assassinés sauvagement. Le garçon s'en sort, mais le maire meurt, faute de soins. Tenma est alors rétrogradé par le directeur de l'hôpital et Eva le quitte. Peu de temps après, le garçon et sa sœur disparaissent. Neuf ans plus tard alors que Tenma est sur le point de devenir le directeur d'hôpital, il est accusé de meurtre qui ont en fait été commis par Johann, ce garçon de 11 ans qu'il avait sauvé. Dès lors l'inspecteur Rünge, un homme de caractère et de confiance prend en charge l'enquête. Il poursuit Tenma sans relâche tandis que ce dernier poursuit Johann ; car Tenma, qui se demande s'il n'a pas sauvé un "Monstre", sait que les meurtres sont "l'œuvre" de son ancien patient.
Naoki Urasawa est de retour chez Kana avec sa toute nouvelle série phare : Asadora ! Urasawa parvient à rendre palpitant le mélange a priori improbable du récit de la vie tumultueuse d'une jeune fille, démarrant en 1959, avec une histoire de monstre godzillesque attaquant le Japon de nos jours. C'est addictif dès les premières pages ! Avec ce récit, on entre à nouveau avec bonheur dans le cinéma d'Urasawa, comme on le ferait dans celui d'un Tarantino !
Kenji est un commerçant lambda qui a repris le magasin familial. La police vient un jour l'interroger sur la disparition de la famille de l'un de ses clients. Le seul indice est un mystérieux symbole dessiné à côté d'une porte. Kenji ne se sent pas particulièrement concerné, jusqu'au jour où Donkey, un ami d'enfance, lui demande s'il se souvient de ce symbole. Kenji explore alors la vie de Donkey, son passé et celui du groupe d'amis dont il faisait partie dans sa jeunesse. Il découvre bientôt l'existence d'une organisation clandestine que dirige l'énigmatique Ami et qui utilise le symbole lié au passé de Kenji comme signe de ralliement. Une série qui n'est plus à présenter ! Ce thriller passionnant s'est vu décerner le prix des éditions Kodansha, fait rarissime puisqu'il était publié par un autre éditeur. En France, le manga de Naoki Urasawa a reçu le prix du meilleur scénario Angoulême 2004 et a été couronné d'un Japan Expo Awards en 2008. Cette nouvelle édition bénéficie de pages couleur et d'une traduction revue.
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