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Gentilhomme poitevin formé dans le meilleur collège Jésuite de France, Descartes est l'un des plus grands génies de son temps. Gloire de la France, celui qu'on appelle le père du rationalisme vécut pourtant plus de la moitié de sa vie en Hollande, pays refuge dans des temps troublés par la guerre de Trente ans et le début de la Fronde. C'est l'histoire de cet homme chaleureux et de sa pensée révolutionnaire pour les sciences et la métaphysique que dépeint cette Bande Dessinée.
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